Am J Chin Med. 1975 Apr; 3(2): 133-42.

Increase of pain threshold as a function of conditionsing electrical stimulation. An experimental study with application to electro-acupuncture for pain suppression.

Holmgren E.

Previous studies have shown that 2 Hz electrical conditioning stimulation of hands and cheeks increased the tooth pain threshold. In the present study the relation between strength of conditioning stimulation and amplitude of pain threshold increase is elucidated. Intense conditioning stimulation, giving subjective beating sensations and extensive muscles twitches, is required to obtain a substantial pain threshold increase. The results are discussed in relation to intensities used in electro-acupuncture and to interindividual variation of the effect. It is suggested that pain relief is obtained due to an inhibitory feed-back mechanism activated, not via low threshold afferents but via high threshold afferents.